Effect of External Electric Field Upon Selected Model Dipeptides

Józef Mazurkiewicz, Piotr Tomasik

Abstract


Effect of external electric field (EEF) of 0.001, 0.005 and 0.01 a.u. upon molecular energy, charge distribution and dipole moments of non-dissociated and inner salt forms of selected dipeptides formed from alanine (Ala), glutamic acid (GluA), and ornithine (Orn) that is, Ala-Ala, Ala-GluA, GluA-Ala, Ala-Orn, Orn-Ala involving α-amino group of Orn and Orn-Ala involving δ-amino group of Orn. For that purpose HyperChem 8.0 software was used together with the AM1 method for optimization of the conformation of the molecules in a computer vacuum.


Keywords


Alanylalanine; Aarboxyglutamylalanine; Alanylglutamic acid; Alanylornithine; α-ornithylalanine; δ-ornithylalanine

Full Text:

PDF

References


Ambroziak, W., & Pietruszko, R. (1993). Metabolic role of aldehyde dehydrogenase. Advances in Experimental Medicine and Biology, 328, 5-15.

Berry, M. N., Grivel, A. R., & Phillips, J. W. (1993). Hypothesis: The electrochemical regulation of metabolism. Pure and Applied Chemistry, 65, 1957-1962.

Crabb, D. W., Bosron, W. F., & Li, T. K. (1987). Ethanol metabolism. Pharmacology & Therapy, 34, 59-73.

Dutreux, D., Notermans, S., Wijtzes, T., Gongora-Nieto, H. M., Barbosa-Canovas, G. V., & Swanson, B. G. (2000). Pulsed electric fields inactivation of attached and free-living Escherichia coli and Listeria innocua under several conditions. International Journal of Food Microbiology, 54, 91-98.

Fiedurek, J. (1999). Influence of pulsed electric field on the spores and oxygen consumption of Aspergillus niger and its citric acid production. Acta Biotechnologica, 19, 179 -186.

Grosse, H. H., Bauer, E., & Berg, H. (1988). Electrostimulation during fermentation. Bioelectrochemistry and Bioenergetics, 20, 279-285.

Harada, A., & Kataoka, K. (2003). Switching by pulse electric field of the elevated enzymatic reaction in the core of polyion complex micelles. Journal of the American Chemical Society, 125, 15306-15307.

Harrison, S. L., Barbosa-Canovas, G. V., & Swanson, B. G., (1997). Saccharomyces cerevisiae structural changes induced by pulsed electric field treatment. LWT-Food Science and Technology, 30, 236-240.

Howl, J. (Ed.). (2005). Peptide synthesis and applications.Totowa, NJ: Humana Press.

Jensen, K. J., Tofteng, S. P., & Pedersen, S. L. (Eds.). (2013). Peptide synthesis and applications (2nd ed.). Totowa, NJ: Humana Press.

Kamiya, K., Boero, M, Shiraishi, K., & Oshiyama, A., (2006). Enol-to-keto tautomerism of peptide groups. J. Phys, Chem., B 110(9), 4443-4450.

Mazurkiewicz, J., & Tomasik, P. (2013b). Effect of external electric field upon selected proteogenic amino acids.Advances in Natural Sciences, 6(4), 1-16.

Mazurkiewicz, J., & Tomasik, P. (2013a). Effect of external electric field to porphin and selected metalloporphyrin systems. Conventional and Alternative Medicin in Science. accepted.

Mazurkiewicz, J., & Tomasik, P. (2010). Contribution to understanding of weak electrical phenomena. Natural Sciences, 2, 1195 -1202.

Mazurkiewicz, J., & Tomasik, P. (2012a). Effect of external electric field upon charge distribution, energy and dipole moment of selected monosaccharide molecules. Natural Sciences, 4, 278-285.

Mazurkiewicz, J., & Tomasik, P. (2012b). Effect of external electric field upon lower alkanols. Advances in Natural Sciences, 5(4), 28-35.

Morozov, Yu. G., Belousova, O. V., Kuznetsov, M. V., Ortega, D., & Parkin, I. P. (2012). Electric field-assisted levitation-jet aerosol synthesis of Ni/NiO nanoparticles.Journal of Materials Chemistry. DOI: 10.1039/c2jm31233f

Munir, Z. A., Ohyanagi, M., Tokita, M., Khor, M., Hirai, T., & Anselmi-Tamburini, U. (Eds.). (2006). Pulse electric current synthesis and processing of materials. New York: J. Wiley.

Nakanishi, K., Tokuda, H., Soga, T., Yoshinaga, T., & Takeda, M. (1988). Effect of electric current on growth and alkohol production by yeast cells. Journal of Fermentation and Bioengimeering. 85, 250-253.

Nechitailo, G., & Gordeev, A. (2001). Effect of artificial electric fields on plants grown under microgravity conditions. Advances in Space Research, 28, 629-631.

Neuberger, A. (1936). Dissociation constants and structures of glutamic acid and its esters. Biochemical Journal, 30, 2085-2094.

Sewald, N., & Jakubke, H. D. (2008). Peptides: Chemistry and Biology. Wiley-VCH, Weinheim.

Tiessie, J., Knox, B. E., Tsong, T. Y., & Wehrle, J. (1981). Synthesis of adenosine triphosphate in respiration – inhibited submitochondrial particles induced by microsecond electric pulses. Proceedings of the National Academy of Sciences USA, 78, 7473-7477.

Tsong, T. Y., & Astumray, R. D. (1986). Absorption and conversion of electric field energy by membrane bound aptases. Bioelectrochemistry and Bioenergetics, 15, 457- 476.




DOI: http://dx.doi.org/10.3968/4294

DOI (PDF): http://dx.doi.org/10.3968/g6145

Refbacks

  • There are currently no refbacks.


Copyright (c)



Share us to:   

Reminder

We are currently accepting submissions via email only.

The registration and online submission functions have been disabled.

Please send your manuscripts to ans@cscanada.net，or  ans@cscanada.org  for consideration. We look forward to receiving your work.

 

 Articles published in Advances in Natural Science are licensed under Creative Commons Attribution 4.0 (CC-BY).

 ADVANCES IN NATURAL SCIENCE Editorial Office

Address: 1055 Rue Lucien-L'Allier, Unit #772, Montreal, QC H3G 3C4, Canada.

Telephone: 1-514-558 6138
Website: Http://www.cscanada.net; Http://www.cscanada.org
E-mail:caooc@hotmail.com; office@cscanada.net

Copyright © 2010 Canadian Research & Development Centre of Sciences and Cultures