Nonlinear Genetics Inbreeding and Genetic Load

Volobuev Andrey Nikolaevich, Romanchuk Peter Ivanovich, Malishev Vladimir Kirikovich

Abstract


Comparison of concepts of occurrence and accumulation of the genetic load in result of inbreeding for a family tree and a population is given. It is shown that for the population the analysis of the genetic load concerns to area of nonlinear genetics. The nonlinear differential equation of the second order being the special case of the Hardy-Weinberg law at presence inbreeding for the population is found. The numerical decision of this equation allowed to find the law of increase of recessive allele frequency in the population is given. Some aspects of the traditional theory of the genetic load are considered.


Keywords


Genetic load; Inbreeding; Hardy-weinberg law; Nonlinear genetics

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References


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DOI: http://dx.doi.org/10.3968/4164

DOI (PDF): http://dx.doi.org/10.3968/g6144

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